Glybenclamide Cas number: 10238-21-8 Molecular Formula：C23H28ClN3O5S

Maikling Paglalarawan:

Numero ng Cas: 10238-21-8

Pangalan ng Kemikal: Glybenclamide

Molecular Formula:C23H28ClN3O5S

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Detalye ng Produkto

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Mga kasingkahulugan

5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]-SULFONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE
5-CHLORO-N-[2-[4-[[[(CYCLOHEXYLAMINO)CARBONYL]AMINO]SULPHONYL]PHENYL]ETHYL]-2-METHOXYBENZAMIDE
5-CHLORO-N-[4-(CYCLOHEXYLUREIDOSULFONYL)PHENETHYL]-2-METHOXYBENZAMIDE
GIBENCLAMIDE
GLIBENCLAMIDE
GLYBENCLAMIDE
GLYBENZCYCLAMIDE
GLYBURIDE
LABOTEST-BB LT00244861
MICRONASE
NP-[2-(5-CHLORO-2-METHOXYBENZAMIDO)ETHYL]BENZENESULFONYL-N'-CYCLOHEXYLUREA
1-((p-(2-(Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl urea
1-((p-(2-(chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl-ure
1-((p-(2-(chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
1-[[p-[2-(5-Chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexylurea
1-[[p-[2-(chloro-o-anisamido)ethyl]phenyl]sulfonyl]-3-cyclohexyl-Urea
5-chloro-n-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2
Abbenclamide
adiab

Pagtutukoy ng Mga Produkto

Temperatura ng pagkatunaw	173-175°C
Densidad	1.1805 (magaspang na pagtatantya)
temp	Inert na kapaligiran, Temperatura ng Kwarto 2-8°C
solubility	ethanol: natutunaw 2mg/mL
aktibidad ng optical	N/A
Hitsura	Puting Crystalline Powder
Kadalisayan	≥98%

Paglalarawan

Ang Glyburide (10238-21-8) ay isang pangalawang henerasyong oral hypoglycemic agent.Gumagana sa pamamagitan ng ATP-dependent na K+ channel (Kir6, KATP) block.1? Inhibits Kir6 currents sa pancreas, na nagdudulot ng pagtaas sa intracellular Ca2+ at insulin secretion.Pinipigilan din ng Glyburide ang mga recombinant na CFTR Cl- channel na may IC50 na 20 μM.2?Cell permeable.